Computational biologist & engineer

Genomics at scale.
Clinical impact at speed.

Turning large-scale multi-omics data into care people can act on.

I’m Aroon Chande — a Staff Bioinformatics Engineer at Color Health. I've spent ten-plus years bridging biology and software across clinical genomics, oncology, and drug development, from CDC pathogen surveillance to the NIH All of Us program.

Now
Staff Bioinformatics Engineer · Color Health
Focus
Clinical & population genomics

About

I build the software and pipelines that turn sequencing and multi-omic data intoreproducible, analysis-ready results — working shoulder-to-shoulder with wet-lab, clinical, and product teams.

At Color, I work on the computational infrastructure returning clinical genetics results for our Virtual Cancer Clinical patients. And previously supported the NIHAll of Us program, helping return genetics results for over 150,000 participants.

Before that, I built analysis platforms for drug development at Seagen, advised the CDC on biosecurity pathogen-surveillance software, and led the COVID-19 Event Risk tool that served 50 million risk predictions to 8 million people.

Selected publications

32 papers · 2014–2026
2021The Impact of Ethnicity and Genetic Ancestry on Disease Prevalence and Risk in ColombiaFrontiers in Genetics · Chande, A.T., Nagar, S.D., Rishishwar, L., Mariño-Ramírez, L., Medina-Rivas, M.A., Valderrama-Aguirre, A., +22020Real-time, interactive website for US-county-level COVID-19 event risk assessmentNature Human Behaviour · Chande, A.T., Lee, S., Harris, M., Nguyen, Q., Beckett, S.J., Hilley, T., +22020Ancestry effects on type 2 diabetes genetic risk inference in Hispanic/Latino populations.BMC Medical Genetics · Chande, A.T., Rishishwar, L., Conley, A.B., Valderrama-Aguirre, A., Medina-Rivas, M.A., Jordan, I.K.2020Ancestry effects on type 2 diabetes genetic risk inference in Hispanic/Latino populations.Genome Biology Evolution · Chande, A.T., Rishishwar, L., Ban, D., Nagar, S.D., Conley, A.B., Rowell, J., +32019STing: accurate and ultrafast genomic profiling with exact sequence matchesNucleic Acids Research · Espitia, H., Chande, A.T., Nagar, S.D., Smith H., Jordan, I.K., Rishishwar, L.2018Bioconda: A sustainable and comprehensive software distribution for the life sciencesNature Methods · Dale, R., Gruning, B., Sjodin, A., Rowe, J., Chapman, B. A., Tomkins-Tinch, C. H., +22017Influence of genetic ancestry and socioeconomic status on type 2 diabetes in the diverse Colombian populations of Chocó and AntioquiaNature Scientific Reports · Chande, A.T., Rowell, J., Rishishwar, L., Conley, A.B., Norris, E.T., Valderrama-Aguirre, A., +2
See all 32 publications →

Experience

Full history in the résumé
May 2022 — Present

Staff Bioinformatics Engineer

Color Health · San Francisco, CA

  • Co-own the computational infrastructure for the NIH All of Us return-of-results program, processing hereditary and pharmacogenetic variants for 200,000+ participants.
  • Led a full refresh of the pharmacogenetics product line for oncology care — combining literature review and computational analysis to prioritize new genes and variants.
  • Design and validate clinical genomics pipelines in close collaboration with lab, clinical, and product teams, turning sequencing data into reproducible, analysis-ready results for patient return-of-results.
Aug 2020 — May 2022

Bioinformatics Scientist

Seagen · Seattle, WA

  • Built an R Shiny analysis platform enabling bench scientists to run ML-based clustering and differential gene expression analysis for drug development.
  • Facilitated analysis of a 30,000+ patient harmonized tumor RNA-seq dataset spanning public (TCGA, GTEx, cBioPortal) and internal data.
  • Served as lead developer and technical lead for an integrated platform supporting RNA-seq, proteomics, and IHC pathology annotation; supported design of new cancer cell lines and genome-wide editing screens.
May 2016 — May 2022

Scientific Advisor

Applied Bioinformatics Laboratory · Atlanta, GA

  • Collaborated with the CDC on biosecurity-focused pathogen surveillance software for efficient reconstruction of pathogen genes and genomes from environmental samples.
  • Developed novel algorithms and high-performance platforms to simplify analysis of NGS data for detecting select agents (anthrax, Ebola, and other highly contagious viral diseases).
Mar — Aug 2020

COVID-19 Pandemic Response

Georgia Institute of Technology · Atlanta, GA

  • Lead developer for the COVID-19 Event Risk Assessment Planning Tool — serving 50 million risk predictions to 8 million users.
  • Lead developer of the MyTest platform for asymptomatic COVID-19 testing — the first campus-wide free testing program in the nation, facilitating over 250,000 tests.
Read the full résumé →